Author: linda
Thu Jan 31 21:57:35 2008

It is incorrect to suggest that the cellulose sulphate trials were stopped on similar grounds to the previously halted Nonoxynol-9 trial - that was found to do more harm than good. By saying this, you imply that cellulose sulphate is known to do more harm than good which is incorrect. There is no evidence at all to suggest that cellulose sulphate is at all harmful and in fact, in over a decade of human studies cellulose sulphate consistently demonstrated a very strong safety profile. Yes, there were HIV sero-conversions within the cellulose sulphate trials that were unexpected, and with the safety of the women participants being the paramount concern, the trials were stopped immediately with the notion that it was better to err on the side of caution and safety until more was known about the HIV conversions within the trial. Further analysis showed that these conversions "were not statistically significant" and no evidence was presented to explain why one site had more HIV conversions than other sites within the trial. No further evidence has yet become available, and in varying African press there were reports that some participants were selling their compound and not strictly adhering to the trial protocol. This also has not been proven, but in the absence of evidence for either case, neither can be said or implied as the reason the trials were halted.




AllAfrica - All the Time

SELECT
SELECT

Most Active Stories

Topics