Health-e (Cape Town)
Anso Thom
18 June 2009
Pharmaceutical giant Tibotec and the non-profit Global Alliance for TB Drug Development (TB Alliance) have teamed up to expedite the development of TMC207, which could become the first TB drug with a new mechanism of action in 40 years.
Interim data from an ongoing Phase II study of TMC207 was recently published in the New England Journal of Medicine. In the placebo-controlled study of 47 patients with multidrug-resistant TB (MDR-TB), it was found that 48 percent of patients receiving TMC207 in combination with standard treatment converted to negative sputum culture after eight weeks compared with 9 percent of those who received placebo and standard treatment.
MDR-TB, which is characterized by resistance to at least two of the most powerful medicines in today's standard, four-drug regimen for drug-susceptible TB, is of particular concern given the rapid rise in the number of cases throughout the world and the difficulties in treating it. There were an estimated 510 0 00 incident cases and 130 000 deaths due to multi-drug resistant TB in 2007.
Under the terms of the agreement announced at the Pacific Health Summit in Seattle this week, Tibotec will continue to develop TMC207 for the treatment of MDR-TB, and on approval, will establish an access program to ensure the compound reaches those in developing countries who are in need. The agreement grants the TB Alliance a royalty-free license for the worldwide development and access to TMC207 in the field of drug-susceptible TB.
In another development the price of a liquid culture test which delivers diagnostic results for drug-resistant tuberculosis much faster than the traditional solid media culture has been cut by 80% increasing the chances of it reaching the poorer high burden countries.
"We are very happy about this price reduction for a needed assay to better and more rapidly detect MDR-TB and XDR-TB. These results are also a direct outcome of a fruitful collaboration with public and private partners such as UNITAID and BD," said Dr. Giorgio Roscigno, FIND (Foundation for Innovative New Diagnostics) Chief Executive Officer.
"During a time of severe economic distress, resources are constrained and high-burden countries face intensified healthcare challenges. This agreement means that it will be possible to make this test more accessible and affordable to those who need it most, which is very encouraging and promising."
UNITAID, which primarily supports health-related projects via 'air tax', also announced that it would make a further U$61-million available to allow the extension of these tests to a further 11 high burden countries. This means that this technology will for the first time be introduced in low-income countries.
BD (Becton, Dickinson and Company), a global medical technology company, and FIND, a Swiss foundation that develops, evaluates and accelerates the implementation of new diagnostic tools for poverty-related diseases, announced the significant price reduction in the cost of liquid culture testing also at the Pacific Health Summit in Seattle this week.
The price reduction, announced five months earlier than anticipated, arises from a November 2007 agreement between BD and FIND. At that time, BD agreed to reduce already below-market prices upon the completion of 3,5-million tests, a milestone achieved this month.
The lower prices will enable more tests to be administered in 39 high-burden countries, as identified by the World Health Organization (WHO).
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REVELATIONS 18 :23
And the light of a candle shall shine no more at all in you; and the voice of the bridegroom and of the bride shall be heard no more at all in you: for your merchants were the great men of the earth; for by your SORCERIES were all nations TRICKED ..
SORCERIES = PHARMACIES
Defeating The Drug Counterfeiters . What about the drugs ? God gave us all the natural herbs to heal us.
PARABLE OF THE GMO GAME AND ITS ORIGINATOR (Satan aka D-Evil ) And Jesus said another parable to them, saying, “ The kingdom of heaven is like a man which planted good seed in his field: But while men slept, his enemy came and sowed tares (GMO / FAKE) among the wheat (NATURAL), and went his way. But when the blade was sprung up, and brought forth fruit, then appeared the tares also. So the servants of the householder came and said to him, Sir, didn’t you plant good seed in thy field ? Where did these weeds (GMO/ FAKE) come from ? The Householder said to them, An enemy (D-Evil) has done this. The servants said to him, Do you want us to pull up the weeds ? The Householder said, No ; we don’t want to hurt the NATURAL plants by accident. Let the GMO /FAKE & NATURAL grow together until the harvest. And in the time of harvest I will say to the reapers, Gather together first the tares (GMO/ FAKE) , and bind them in bundles to burn them (In The Lake Of Fire & Brimstone). Then gather the wheat into my barn. (PARADISE) “ [Matthew 13:24 -30 - Paraphrased] ROACH GENES IN CORN [http://ixquick.com/do/metasearch.pl?query=Roach+genes+in+corn&cat=web&pl=f f&language=english]
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God Bless Africa – God Bless Us – Pray For Each Other
[This inspiring poem was featuring in the movie “Coach Carter ”]
Our Deepest Fear Is Not That We Are Inadequate, Our Deepest Fear Is That We Are Powerful Beyond Measure. It Is Our Light , Not Our Darkness That Most Frightens Us.
We Ask Ourselves, Who Am I To Be Brilliant, Gorgeous, Talented, And Fabulous ?
Actually Who Are We Not To Be ? You Are A Child Of God.
Your Playing Small Doesn’t Serve The World.
There Is Nothing Enlightened About Shrinking So That Other People Won’t Feel Insecure Around You.
We Are All Meant To Shine, As Children Do.
We Were Born To Make Manifest The Glory Of God That Is Within Us.
It’s Not Just In Some Of Us; It’s In Everyone.
And When We Let Our Own Light Shine We Unconsciously Give Other People Permission To Do The Same.
And As We Are Liberated From Our Own Fear, Our Presence Automatically Liberates Others
- Marianne Williamson -
[NOTE – BEING AFRAID AND REFUSING TO GET INVOLVED WON’T STOP US FROM DYING. BUT BEING AFRAID CAN PREVENT US FROM LIVING]
(Nkosi Sikeleli Africa )
God bless Africa May her glory be lifted high Hear our petitions .
God bless us, Your children God we ask You to protect our nation Intervene and end all conflicts Protect us, protect our nation, our nation.
From the blue of our heaven, From the depths of our sea, Over our eternal mountain ranges, Where the cliffs give answer.
Sounds the call to come together, And united we shall stand, Let us live and strive for freedom, In South Africa our land.
[Enoch Mankayi Sontonga]
[http://www.infowars.com/infowars.asx] / [gcnlive.com] / [http://alexjonesringtones.net/]
WAKE UP ! STAY UP MY BROTHERS & SISTERS ! BE SELF-SUFFICIENT IN THE KINGDOM OF HEAVEN.
- Life Is a Game. Have Fun. [ Luke 18:17 / Isaiah 11:6 ]