Transport Minister Mohamed Rashad Matini accepted on Wednesday the resignation of Ali Hussein, head of the Egyptian Company for Metro Management and Operation, in response to the demands of the metro workers.
Following the resignation, the workers suspended their strike as one of their demands had been met.
The demands of the strike included improved healthcare, enhanced metro security as well as financial benefits.
Workers began their strike on Tuesday, some of them staying overnight in metro stations. They closed the gates in the face of the public and drivers abstained from operating the trains.
Egypt's Transport Minister had initially refused to sack the head of the metro company claiming that such action would undermine Hussein's history.
The underground in Egypt transfers about two million passengers daily and is especially vital in the neighborhood of Helwan, located in South Cairo.
Other transportation means were affected by the strike where crowds flooded the streets attempting to reach destinations in light of the suspension of their usual carrier.