Mali's President Ibrahim Boubakar Keita has fired prime minister Oumar Tatam Ly and replaced him with urban planning minister Moussa Mara.
An official statement announced the sacking and the resignation of Ly's government on Sunday.
Keita has ordered Mara to form a new government, the statement said, but it did not explain the reasons for the departure of the previous one.
Mara, 39 - an accountant and mayor of part of the capital, Bamako - was a candidate in last year's presidential election, winning 1.5 per cent of the vote, and leads the Yelema (Change) party that he founded in 2010.
He is the son of former justice minister Joseph Mara, who was imprisoned five years under military dictator Moussa Traoré in the 1970s.
Ly, 50, is a banker by propfession, and was appointed by Keita following his election victory which in turn followed a French military intervention that put a stop to a rebellion by Islamic fundamentalists and Tuareg separatists.