There is concern about the effects of irrational use of antibiotics. This is not only because of the issue of antimicrobial resistance but importantly about the effect of antibiotics on the gut microbiota. The digestive tract especially the large intestine is the habitat for millions of microbes living in concert with several functions of the body. Antibiotics have been very useful in treating and controlling infections with positive impact of standard of living.
However, our control over microbial disease is diminishing. Langdon et al. The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutics modulation. Genome Medicine (2016). 8:39.
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