Thirteen deaths were recorded from the virus on Thursday bringing the total number of confirmed deaths from the virus to 616.
The Ondo commissioner for health, Wahab Adegbenro, was reported to have died from the virus on Thursday.
There was a drop in the number of confirmed cases reported on Thursday (626) compared to what was reported on Wednesday (790).
Wednesday's figure was the country's highest yet.
The health agency in a tweet Thursday night said the new cases were reported in 20 states.
These are Lagos, Federal Capital Territory (FCT), Oyo, Edo, Kwara, Abia, Ogun, Ondo, Rivers, Osun, Akwa Ibom, Delta, Enugu, Kaduna, Plateau, Borno, Bauchi, Adamawa, Gombe, and Sokoto States.
All the reporting states already had at least a case of the virus.
As of the time of reporting, 35 states and the FCT have recorded at least a case of the disease. Only one state, Cross River, is yet to officially report any case of the virus although there are controversies about it.
Lagos remains the epicentre for the disease in the country. Zamfara has not reported any new confirmed case in the past 45 days.
"Till date, 27, 110 cases have been confirmed 10,801 cases have been discharged and 616 deaths have been recorded in 35 states and the Federal Capital Territory," the NCDC stated.
The 626 new cases were reported from 20 states: Lagos - 193,FCT - 85, Oyo - 41, Edo - 38, Kwara - 34, Abia - 31, Ogun - 29, Ondo - 28, Rivers - 26, Akwa Ibom - 18, Delta - 18, Enugu - 15, Kaduna - 13, Plateau -11, Borno - 8, Bauchi - 7, Adamawa - 5, Gombe - 4 and Sokoto - 1.
Since the onset of the COVID-19 outbreak in Nigeria in February, NCDC said 141, 525 samples have so far been tested.
As of the time of reporting, there are 15, 693 active cases of COVID-19 in the country, while 10, 801 have recovered and have been discharged.
A breakdown of the 27, 110 confirmed cases shows that Lagos State has so far reported 10, 823 cases, followed by FCT - 2, 020, Oyo - 1, 432, Kano - 1, 257, Edo - 1, 203, Delta - 1, 149, Rivers - 1, 114, Ogun -898, Kaduna - 818, Katsina - 578, Bauchi - 512, Gombe - 511, Borno - 501, Ebonyi - 483, Plateau - 393, Ondo - 353, Imo - 352, Abia - 451, Enugu - 342, Jigawa - 318, Kwara - 369, Bayelsa - 324, Nasarawa - 213, Sokoto - 152, Osun - 148, Niger - 116, Akwa Ibom - 104, Adamawa - 89, Kebbi - 81, Zamfara - 76, Anambra - 73, Benue - 65, Yobe - 61, Ekiti - 43, Taraba - 19 and Kogi - 4.
The Director-General, NCDC, Chikwe Ihekweazu, during the Presidential Task Force briefing on Thursday, said "Statistics show the major drivers of COVID-19 spread are the younger populations, however people with underlying medical conditions and the elderly are most vulnerable."
He said people over 50 years and those with preexisting medical conditions like diabetes are at a higher risk of complications due to COVID-19.
"We must take responsibility to keep them safe," he added.