Africa: Coronavirus - a Single 'Escape Mutant' Shouldn't Render a Vaccine Useless

analysis

Several coronavirus variants have emerged in recent weeks that have got scientists worried. The variants, which were first identified in the UK (B117), South Africa (B1351) and Brazil (P1 and P2), have several mutations in the spike protein - the little projections on the surface of the virus that help it latch onto human cells. This protein is the target for all the COVID vaccines currently being rolled out. So will the vaccines protect us from these new variants?

Viruses are often not very good at making identical copies of themselves. This means that each time they replicate, changes or "mutations" in their genetic sequence can occur. Most of these mutations are harmless and have no effect on the virus. However, a small minority may allow the virus to avoid being recognised by components of our immune system. Such mutations are known as "escape mutants".

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