New York/Copenhagen — UNICEF today announced that it has issued an emergency tender for the procurement of mpox vaccines. Vaccines can play a critical role in containing the mpox outbreak which was declared a public health emergency by both the Africa Centres for Disease Control and Prevention (Africa CDC) and the World Health Organization (WHO).
The UNICEF tender is issued to help secure mpox vaccines for the hardest hit countries in collaboration with Africa CDC, Gavi, the Vaccine Alliance, WHO, the Pan American Health Organization and other partners. This collaboration to increase access and timely allocation also includes working together to facilitate donations of vaccines from existing stockpiles in high-income countries with the aim of containing the ongoing transmission of mpox.
Under the emergency tender, UNICEF will set up conditional supply agreements with vaccine manufacturers. This will enable UNICEF to purchase and ship vaccines without delay once countries and partners have secured financing, confirmed demand and readiness, and the regulatory requirements for accepting the vaccines are in place. WHO is currently reviewing the information submitted by manufacturers on 23 August and is expected to complete its review for Emergency Use Listing by mid-September.
More than 18,000 suspected cases of mpox, including 629 deaths, have been reported this year in the Democratic Republic of the Congo which is at the epicentre of the crisis. Four out of five deaths have been in children.
"Addressing the current mpox vaccine shortage and delivering vaccines to communities who need them now is of paramount importance. There is also a pressing need for a universal and transparent allocation mechanism to ensure equitable access to mpox vaccines," said Director of UNICEF Supply Division Leila Pakkala.
"As we confront the ongoing Mpox outbreak, the timely procurement and distribution of vaccines is crucial to protecting the most vulnerable populations, particularly in the hardest-hit regions. This emergency tender is a critical step forward in our collective effort to control the spread of this disease. Africa CDC is committed to ensuring that vaccines are allocated swiftly and equitably across the continent, in partnership with UNICEF, Gavi, WHO, and other key stakeholders. Our unified response is essential to curbing the impact of this public health emergency and safeguarding the health and well-being of our communities," said Dr. Jean Kaseya, Director General of Africa CDC.
"With several partners working on securing access to supply, today's announcement represents an important step in this emergency, enabling UNICEF to purchase and deliver vaccines after Gavi and other partners make funding available and sign purchase or donation agreements with manufacturers for the most immediate dose needs," said Dr Derrick Sim, interim Chief Vaccine Programmes and Markets Officer at Gavi, the Vaccine Alliance. "Securing access to supply and financing, delivering doses, and in parallel ensuring countries are ready to administer them, are all vital actions that need to be conducted rapidly but thoroughly, and in a coordinated manner. We welcome this tender as another positive step our Alliance and Africa CDC are taking in this response."
"A swift, coordinated, and equitable response is critical to controlling the current mpox emergency and preventing future ones," said Dr Maria Van Kerkhove, WHO incident manager for the global mpox response and acting Director for Epidemic and Pandemic Preparedness and Prevention. "All of us must act decisively now or risk allowing mpox to spread further and become an even greater global threat. In an interconnected world, the fight against mpox - as with other infectious diseases and health threats -- cannot be waged alone., WHO is glad to partner with UNICEF, Gavi, Africa CDC, other partners and affected countries to get life-saving tools to people in need."
The emergency tender is designed to secure immediate access to available mpox vaccines as well as to expand production. Depending on demand, production capacity of manufacturers and funding, agreements for up to 12 million doses through 2025 can be put in place.
Vaccines are one of several tools used to interrupt transmission and to protect children and communities against mpox. Africa CDC, Gavi, UNICEF, WHO, and partners are also prioritizing infection prevention and control, and risk communication and community engagement. As part of this, UNICEF is deploying personal protection equipment, diagnostic tests, medical treatment kits, hygiene supplies and tents to countries at the forefront of the crisis. These supplies support a host of medical countermeasures such as treatment, case isolation and surveillance.
UNICEF is the world's largest single vaccine buyer, procuring more than 2 billion doses of vaccines annually for routine child immunization and outbreak response on behalf of nearly 100 countries.
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About Africa CDC
The Africa Centres for Disease Control and Prevention (Africa CDC) is a continental autonomous public health agency of the African Union that supports member states in efforts to strengthen health systems and improve surveillance, emergency response, and prevention and control of diseases.
Learn more at: http://www.africacdc.org and connect with us on LinkedIn, Twitter, Facebook and YouTube
About UNICEF
UNICEF works in some of the world's toughest places, to reach the world's most disadvantaged children. Across more than 190 countries and territories, we work for every child, everywhere, to build a better world for everyone.
Follow UNICEF on Twitter, Facebook, Instagram and YouTube
About Gavi, the Vaccine Alliance
Gavi, the Vaccine Alliance is a public-private partnership that helps vaccinate more than half the world's children against some of the world's deadliest diseases. The Vaccine Alliance brings together developing country and donor governments, the World Health Organization, UNICEF, the World Bank, the vaccine industry, technical agencies, civil society, the Bill & Melinda Gates Foundation and other private sector partners. View the full list of donor governments and other leading organisations that fund Gavi's work here.
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Since its inception in 2000, Gavi has helped to immunise a whole generation - over 1 billion children - and prevented more than 17.3 million future deaths, helping to halve child mortality in 78 lower-income countries. Gavi also plays a key role in improving global health security by supporting health systems as well as funding global stockpiles for Ebola, cholera, meningococcal and yellow fever vaccines. After two decades of progress, Gavi is now focused on protecting the next generation, above all the zero-dose children who have not received even a single vaccine shot. The Vaccine Alliance employs innovative finance and the latest technology - from drones to biometrics - to save lives, prevent outbreaks before they can spread and help countries on the road to self-sufficiency. Learn more at www.gavi.org and connect with us on Facebook and X (Twitter).
About WHO
Dedicated to the well-being of all people and guided by science, the World Health Organization leads and champions global efforts to give everyone, everywhere an equal chance at a safe and healthy life. We are the UN agency for health that connects nations, partners and people on the front lines in 150+ locations - leading the world's response to health emergencies, preventing disease, addressing the root causes of health issues and expanding access to medicines and health care. Our mission is to promote health, keep the world safe and serve the vulnerable. www.who.int
