A Common Carbohydrate May Hold Key to TB Treatment

Curdlan is a popular carbohydrate in the food industry. Its name is derived from the word "curdle", and as it suggests, it's widely used as a thickener and stabiliser in everything from sausages to milk substitutes.

More recently, it has caught the eye of the pharmaceutical industry, writes Admire Dube for The Conversation. That's because curdlan, itself produced by bacteria, is able to trigger an antibacterial response in a range of environments and organisms. Among other uses, researchers are looking at curdlan as a possible treatment for cancers and other diseases.

One of those diseases is tuberculosis (TB), the infection responsible for killing more people than any other infectious disease in human history. South Africa has one of the world's highest TB burdens - along with 29 other countries including India and China. These countries contribute 86% of the globe's 10 million annual TB cases.

InFocus

Tuberculosis researchers working in a Biosafety Level 3 Lab at the University of Cape Town in 2017.

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