The Africa Business: Health Forum (ABHF) aims to strengthen partnerships, promote an ongoing dialogue between the African private and public sectors, and foster opportunities for the private sector to contribute towards the collective efforts of key stakeholders in strengthening national health systems in Africa. Healthy populations matter for Africa’s long-term growth and sustainable development, and can be an avenue for economic gains through raised productivity, job creation and reduction of inequalities. Africa’s healthcare systems demand significant investments to meet the needs of their growing populations, changing patterns of diseases and the internationally-agreed development goals. The ABHF will bring together the participation of African leadership – governments, chief executive officers, business and finance leaders, philanthropists and high level representation from the African Union and United Nations system. Outputs from the Forum are expected to help shape and drive a health-centric agenda for Africa’s accelerated development. The Forum itself will culminate in the launch of a number of instruments to help scale-up investments and partnerships on health.