In South Sudan, decades of civil war have left the health care system severely depleted. For this reason, South Sudan's strategy to fight tuberculosis now draws on remote communities themselves to detect and treat cases of tuberculosis. Community health workers called "hands" and "peer educators" visit homes of people who are unable to travel or live too far from the nearest health facility. Since 2009, more than 11000 TB patients were diagnosed and treated in South Sudan through this program, which is supported by the Global Fund.

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