Citizens of several sub-Saharan countries are widely divided over their level of trust in Covid-19 vaccinations. This emerged from ground-breaking analysis of vaccine sentiment on social media in six countries: South Africa, Ghana, Kenya, Senegal, Nigeria and Tanzania. The Centre for Analytics and Behavioural Change (CABC) at UCT gathered data about the overall vaccine conversation on social media from mid-June to mid-August this year. The CABC's findings were geo-filtered to locate their origin in one of these six countries.